burst suppression

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periods of generalized activity (the burst) interspersed with periods of generalized voltage attenuation

clinical significance

Two most common clinical implications:

  • diffuse brain injury; most commonly this is anoxic, as seen from prolonged resuscitation post-MI
  • pharmacologically induced. Typical agents are versed drip, phenobarbitol, or propofol. The depth of suppression may be measured as the percent of time spent in suppression. Sufficient doses will result in 100 percent suppression.